Immunotherapies targeting tumor vasculature: challenges and opportunities

Immunotherapies targeting tumor vasculature: challenges and opportunities

Angiogenesis is a hallmark of cancer biology, and neoadjuvant therapies targeting either tumor vasculature or VEGF signaling have been developed to treat solid malignant tumors. However, these therapies induce complete vascular depletion leading to hypoxic niche, drug resistance, and tumor recurrenc...

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Bibliographic Details
Main Authors: Hassan Dianat-Moghadam, Reza Nedaeinia, Mohsen Keshavarz, Mehdi Azizi, Mohammad Kazemi, Rasoul Salehi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
angiogenesis
biomarker
hypoxia
immunotherapy
tumor vasculature
nanoparticles
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1226360/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1226360/full

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