De novo design and experimental characterization of ultrashort self-associating peptides.

Self-association is a common phenomenon in biology and one that can have positive and negative impacts, from the construction of the architectural cytoskeleton of cells to the formation of fibrils in amyloid diseases. Understanding the nature and mechanisms of self-association is important for modul...

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Bibliographic Details
Main Authors: James Smadbeck, Kiat Hwa Chan, George A Khoury, Bo Xue, Robert C Robinson, Charlotte A E Hauser, Christodoulos A Floudas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4091692?pdf=render