Lack of evidence for changing virulence of HIV-1 in North America.

Several long-term cohort studies and in-vitro fitness assays have resulted in inconsistent reports on changes in HIV-1 virulence, including reports of decreasing, stable, and increasing virulence over the course of the AIDS pandemic. We tested the hypothesis of changing HIV-1 virulence by examining...

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Bibliographic Details
Main Authors: Joshua T Herbeck, Geoffrey S Gottlieb, Xiuhong Li, Zheng Hu, Roger Detels, John Phair, Charles Rinaldo, Lisa P Jacobson, Joseph B Margolick, James I Mullins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2211407?pdf=render