Cell cycle-dependent and independent mating blocks ensure fungal zygote survival and ploidy maintenance.

To ensure genome stability, sexually reproducing organisms require that mating brings together exactly 2 haploid gametes and that meiosis occurs only in diploid zygotes. In the fission yeast Schizosaccharomyces pombe, fertilization triggers the Mei3-Pat1-Mei2 signaling cascade, which represses subse...

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Bibliographic Details
Main Authors: Aleksandar Vještica, Melvin Bérard, Gaowen Liu, Laura Merlini, Pedro Junior Nkosi, Sophie G Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001067