Immortalized human myotonic dystrophy type 1 muscle cell lines to address patient heterogeneity

Immortalized human myotonic dystrophy type 1 muscle cell lines to address patient heterogeneity

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Summary: Historically, cellular models have been used as a tool to study myotonic dystrophy type 1 (DM1) and the validation of therapies in said pathology. However, there is a need for in vitro models that represent the clinical heterogeneity observed in patients with DM1 that is lacking in classica...

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Bibliographic Details
Main Authors: Judit Núñez-Manchón, Júlia Capó, Alicia Martínez-Piñeiro, Eduard Juanola, Jovan Pesovic, Laura Mosqueira-Martín, Klaudia González-Imaz, Pau Maestre-Mora, Renato Odria, Dusanka Savic-Pavicevic, Ainara Vallejo-Illarramendi, Kamel Mamchaoui, Anne Bigot, Vincent Mouly, Mònica Suelves, Gisela Nogales-Gadea
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:iScience
Subjects:
Health sciences
Biological sciences
Molecular biology
Epigenetics
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224011520

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http://www.sciencedirect.com/science/article/pii/S2589004224011520

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