Concomitant Immunotherapy and Metastasis-Directed Radiotherapy in Upper Tract Urothelial Carcinoma: A Biomarker-Driven, Original, Case-Based Proof-of-Concept Study

Concomitant Immunotherapy and Metastasis-Directed Radiotherapy in Upper Tract Urothelial Carcinoma: A Biomarker-Driven, Original, Case-Based Proof-of-Concept Study

Metastatic upper tract urothelial carcinoma (mUTUC) has a poor prognosis. Immune checkpoint inhibitors (ICIs) have demonstrated efficacy in patients with metastatic urothelial carcinoma. However, data supporting the use of ICIs in patients with mUTUC are limited. A promising synergy between ICI and...

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Bibliographic Details
Main Authors: Gaetano Pezzicoli, Francesco Salonne, Vittoria Musci, Federica Ciciriello, Stefania Tommasi, Rosanna Lacalamita, Alfredo Zito, Sara Antonia Allegretta, Antonio Giovanni Solimando, Mimma Rizzo
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Clinical Medicine
Subjects:
upper tract urothelial carcinoma
immune-checkpoint inhibitors
radiotherapy
abscopal effect
genomic profiling
Online Access:https://www.mdpi.com/2077-0383/12/24/7761

Internet

https://www.mdpi.com/2077-0383/12/24/7761

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