Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α

Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α

Abstract Background Medulloblastoma (MB) is the most common malignant brain tumor in children. Approximately one-third of MB patients remain incurable. Understanding the molecular mechanism of MB tumorigenesis is, therefore, critical for developing specific and effective treatment strategies. Our pr...

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Bibliographic Details
Main Authors: Biao Gong, Duancheng Guo, Chaonan Zheng, Zhen Ma, Jie Zhang, Yanghui Qu, Xinhua Li, Gen Li, Li Zhang, Yuan Wang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Neuroinflammation
Subjects:
Medulloblastoma
Astrocytes
C3a
TNF-α
Online Access:https://doi.org/10.1186/s12974-022-02516-9

Internet

https://doi.org/10.1186/s12974-022-02516-9

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