Preclinical models of acute liver failure: a comprehensive review

Acute liver failure is marked by the rapid deterioration of liver function in a previously well patient over period of days to weeks. Though relatively rare, it is associated with high morbidity and mortality. This makes it a challenging disease to study clinically, necessitating reliance on preclin...

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Bibliographic Details
Main Authors: Joshua Hefler, Braulio A. Marfil-Garza, Rena L. Pawlick, Darren H. Freed, Constantine J. Karvellas, David L. Bigam, A. M. James Shapiro
Format: Article
Language:English
Published: PeerJ Inc. 2021-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12579.pdf