USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathwayResearch in context

Background: USP11 is an ubiquitin-specific protease that plays an important role in tumor progression via different mechanisms. However, the expression and prognostic significance of USP11 in colorectal cancer (CRC) remain unknown. Methods: Bioinformatics analyses, qRT-PCR, western blotting, and imm...

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Bibliographic Details
Main Authors: Hongze Sun, Baochi Ou, Senlin Zhao, Xueni Liu, Liwei Song, Xisheng Liu, Rangrang Wang, Zhihai Peng
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419305754