Targeting KRAS: Crossroads of Signaling and Immune Inhibition

Mutations of RAS are commonly seen in human cancers, especially in lung, colorectal, and pancreatic adenocarcinoma. Despite huge effort for decades, targeting RAS mutations has been ‘‘undruggable’’ because of the molecular instability of RAS protein inhibition. However, the recent discovery of the K...

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Bibliographic Details
Main Authors: Shumei Kato, Yu Fujiwara, David S. Hong
Format: Article
Language:English
Published: Innovative Healthcare Institute 2022-08-01
Series:Journal of Immunotherapy and Precision Oncology
Subjects:
Online Access:https://theijpt.org/doi/pdf/10.36401/JIPO-22-5