The adult cystic fibrosis airway microbiota is stable over time and infection type, and highly resilient to antibiotic treatment of exacerbations.

The adult cystic fibrosis airway microbiota is stable over time and infection type, and highly resilient to antibiotic treatment of exacerbations.

Cystic fibrosis (CF) is characterized by defective mucociliary clearance and chronic airway infection by a complex microbiota. Infection, persistent inflammation and periodic episodes of acute pulmonary exacerbation contribute to an irreversible decline in CF lung function. While the factors leading...

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Bibliographic Details
Main Authors: Anthony A Fodor, Erich R Klem, Deirdre F Gilpin, J Stuart Elborn, Richard C Boucher, Michael M Tunney, Matthew C Wolfgang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3458854?pdf=render

Internet

http://europepmc.org/articles/PMC3458854?pdf=render

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