Effect on cardiac function among patients with type 2 diabetes following high-dose mineralocorticoid receptor antagonist using echocardiography; data from the MIRAD randomized clinical trial

Effect on cardiac function among patients with type 2 diabetes following high-dose mineralocorticoid receptor antagonist using echocardiography; data from the MIRAD randomized clinical trial

Abstract Background Early heart failure prevention is central in patients with type 2 diabetes, and mineralocorticoid receptor antagonists (MRAs) have shown to improve prognosis. We investigated the effect of high-dose MRA, eplerenone, on cardiac function and structure in patients with type 2 diabet...

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Bibliographic Details
Main Authors: Niels H. Brandt-Jacobsen, Marie Louise Johansen, Jon J. Rasmussen, Morten Dalsgaard, Thomas Kumler, Jens Faber, Patrick Rossignol, Morten Schou, Caroline Kistorp
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Cardiovascular Disorders
Subjects:
Mineralocorticoid receptor antagonist
High-dose eplerenone
Global longitudinal strain
Systolic and diastolic function
Online Access:https://doi.org/10.1186/s12872-023-03183-1

Internet

https://doi.org/10.1186/s12872-023-03183-1

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