Geranylgeranyl diphosphate synthase: Role in human health, disease and potential therapeutic target

Abstract Geranylgeranyl diphosphate synthase (GGDPS), an enzyme in the isoprenoid biosynthesis pathway, is responsible for the production of geranylgeranyl pyrophosphate (GGPP). GGPP serves as a substrate for the post‐translational modification (geranylgeranylation) of proteins, including those belo...

Full description

Bibliographic Details
Main Authors: Molly E. Muehlebach, Sarah A. Holstein
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1167