Geranylgeranyl diphosphate synthase: Role in human health, disease and potential therapeutic target
Abstract Geranylgeranyl diphosphate synthase (GGDPS), an enzyme in the isoprenoid biosynthesis pathway, is responsible for the production of geranylgeranyl pyrophosphate (GGPP). GGPP serves as a substrate for the post‐translational modification (geranylgeranylation) of proteins, including those belo...
Main Authors: | Molly E. Muehlebach, Sarah A. Holstein |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
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Series: | Clinical and Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/ctm2.1167 |
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