Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation

Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation

Summary: The production of type 1 conventional dendritic cells (cDC1s) requires high expression of the transcription factor IRF8. Three enhancers at the Irf8 3′ region function in a differentiation stage-specific manner. However, whether and how these enhancers interact physically and functionally r...

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Bibliographic Details
Main Authors: Takaya Yamasaki, Akira Nishiyama, Nagomi Kurogi, Koutarou Nishimura, Shion Nishida, Daisuke Kurotaki, Tatsuma Ban, Jordan A. Ramilowski, Keiko Ozato, Atsushi Toyoda, Tomohiko Tamura
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724004352

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http://www.sciencedirect.com/science/article/pii/S2211124724004352

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