Pharmacological Characterization of Purified Full-Length Dopamine Transporter from <i>Drosophila melanogaster</i>

Pharmacological Characterization of Purified Full-Length Dopamine Transporter from <i>Drosophila melanogaster</i>

The dopamine transporter (DAT) is a member of the neurotransmitter:sodium symporter (NSS) family, mediating the sodium-driven reuptake of dopamine from the extracellular space thereby terminating dopaminergic neurotransmission. Our current structural understanding of DAT is derived from the resoluti...

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Bibliographic Details
Main Authors: Ciara Frances Pugh, Brian Thomas DeVree, Solveig Gaarde Schmidt, Claus Juul Loland
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
dopamine transporter
protein purification
molecular pharmacology
scintillation proximity assay
radioligand
dopamine binding
Online Access:https://www.mdpi.com/2073-4409/11/23/3811

Internet

https://www.mdpi.com/2073-4409/11/23/3811

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