Pathological response and safety of FOLFOXIRI for neoadjuvant treatment of high-risk relapsed locally advanced colon cancer: study protocol for a single-arm, open-label phase II trial

Introduction Neoadjuvant chemotherapy (NAC) has been demonstrated effective in several tumours, but its benefit has not yet been elucidated in colorectal cancer, especially locally advanced colorectal cancer (LACRC).Methods and analysis This is a single-arm, open-label, prospective phase II explorat...

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Bibliographic Details
Main Authors: Xiaorong Chen, Ziqiang Wang, Peng Cao, Meng Qiu, Weibing Leng, YuWen Zhou, Yongyang Yu, Wenjian Meng
Format: Article
Language:English
Published: BMJ Publishing Group 2023-01-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/1/e062659.full