TP53-related signature for predicting prognosis and tumor microenvironment characteristics in bladder cancer: A multi-omics study

TP53-related signature for predicting prognosis and tumor microenvironment characteristics in bladder cancer: A multi-omics study

Background: The tumor suppressor gene TP53 is frequently mutated or inactivated in bladder cancer (BLCA), which is implicated in the pathogenesis of tumor. However, the cellular mechanisms of TP53 mutations are complicated, yet well-defined, but their clinical prognostic value in the management of B...

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Bibliographic Details
Main Authors: Yuting Tao, Xia Li, Yushan Zhang, Liangyu He, Qinchen Lu, Yaobang Wang, Lixin Pan, Zhenxing Wang, Chao Feng, Yuanliang Xie, Zhiyong Lai, Tianyu Li, Zhong Tang, Qiuyan Wang, Xi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Genetics
Subjects:
bladder cancer
TP53
immunosuppression
tumor microenvironment
multi-omics studies
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1057302/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1057302/full

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