Differential replication dynamics for large and small <it>Vibrio </it>chromosomes affect gene dosage, expression and location
<p>Abstract</p> <p>Background</p> <p>Replication of bacterial chromosomes increases copy numbers of genes located near origins of replication relative to genes located near termini. Such differential gene dosage depends on replication rate, doubling time and chromosome...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-11-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/9/559 |