Shape of the first mitotic spindles impacts multinucleation in human embryos

Shape of the first mitotic spindles impacts multinucleation in human embryos

Abstract During human embryonic development, early cleavage-stage embryos are more susceptible to errors. Studies have shown that many problems occur during the first mitosis, such as direct cleavage, chromosome segregation errors, and multinucleation. However, the mechanisms whereby these errors oc...

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Bibliographic Details
Main Authors: Yuki Ono, Hiromitsu Shirasawa, Kazumasa Takahashi, Mayumi Goto, Takahiro Ono, Taichi Sakaguchi, Motonari Okabe, Takeo Hirakawa, Takuya Iwasawa, Akiko Fujishima, Tae Sugawara, Kenichi Makino, Hiroshi Miura, Noritaka Fukunaga, Yoshimasa Asada, Yukiyo Kumazawa, Yukihiro Terada
Format: Article
Language:English
Published: Nature Portfolio 2024-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49815-8

Internet

https://doi.org/10.1038/s41467-024-49815-8

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