Differential vulnerability of neuronal subpopulations of the subiculum in a mouse model for mesial temporal lobe epilepsy

Differential vulnerability of neuronal subpopulations of the subiculum in a mouse model for mesial temporal lobe epilepsy

Selective loss of inhibitory interneurons (INs) that promotes a shift toward an excitatory predominance may have a critical impact on the generation of epileptic activity. While research on mesial temporal lobe epilepsy (MTLE) has mostly focused on hippocampal changes, including IN loss, the subicul...

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Bibliographic Details
Main Authors: Julia Franz, Nicole Barheier, Henrike Wilms, Susanne Tulke, Carola A. Haas, Ute Häussler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
parvalbumin
neuropeptide Y
calretinin
FluoroJade C
intrahippocampal kainate
dorso-ventral axis
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1142507/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1142507/full

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