Resistance to DNA repair inhibitors in cancer
The DNA damage response (DDR) represents a complex network of proteins which detect and repair DNA damage, thereby maintaining the integrity of the genome and preventing the transmission of mutations and rearranged chromosomes to daughter cells. Faults in the DDR are a known driver and hallmark of c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-11-01
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Series: | Molecular Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/1878-0261.13224 |