Proof-of-Concept Double-Blind Placebo-Controlled Trial Measuring Cartilage Composition in Early Rheumatoid Arthritis under TNF-α-Inhibitor Therapy

Proof-of-Concept Double-Blind Placebo-Controlled Trial Measuring Cartilage Composition in Early Rheumatoid Arthritis under TNF-α-Inhibitor Therapy

Low levels of delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) values are indicative of cartilage degeneration. Patients with early rheumatoid arthritis are known to have low dGEMRIC values due to inflammatory activity. The additional effect of biological disease-modifyi...

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Bibliographic Details
Main Authors: Miriam Frenken, Benedikt Ostendorf, Ralph Brinks, Christoph Schleich, Lena M. Wilms, Stefan Vordenbäumen, Anja Müller-Lutz, Jutta G. Richter, Oliver Sander, Gerald Antoch, Matthias Schneider, Xenofon Baraliakos, Daniel B. Abrar, Philipp Sewerin
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Journal of Clinical Medicine
Subjects:
rheumatoid arthritis
therapeutics
articular cartilage
radiology
musculoskeletal system
Online Access:https://www.mdpi.com/2077-0383/12/6/2306

Internet

https://www.mdpi.com/2077-0383/12/6/2306

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