Blimp-1 Contributes to the Development and Function of Regulatory B Cells

Blimp-1 Contributes to the Development and Function of Regulatory B Cells

Regulatory B cells (Bregs) are a B cell subset that plays a suppressive role in immune responses. The CD19+CD1dhiCD5+ Bregs that can execute regulatory functions via secreting IL-10 are defined as B10 cells. Bregs suppress autoimmune and inflammatory diseases, whereas they exacerbate infectious dise...

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Bibliographic Details
Main Authors: Ying-Hsiu Wang, Dong-Yan Tsai, Yi-An Ko, Tsan-Tzu Yang, I-Ying Lin, Kuo-Hsuan Hung, Kuo-I Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
regulatory B cells
B10 cells
Blimp-1
IL-10
Candida albicans
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01909/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01909/full

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