Comprehensive Analysis of N6-Methyladenosine (m6A) Methylation in Neuromyelitis Optica Spectrum Disorders

Comprehensive Analysis of N6-Methyladenosine (m6A) Methylation in Neuromyelitis Optica Spectrum Disorders

Background: N6-Methyladenosine (m6A) methylation is the most prevalent internal posttranscriptional modification on mammalian mRNA. But its role in neuromyelitis optica spectrum disorders (NMOSD) is not known.Aims: To explore the mechanism of m6A in NMOSD patients.Methods: This study assessed the m6...

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Bibliographic Details
Main Authors: Hong Yang, Yi-Fan Wu, Jie Ding, Wei Liu, De-Sheng Zhu, Xia-Feng Shen, Yang-Tai Guan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Genetics
Subjects:
neuromyelitis optica spectrum disorder
immune homeostasis
N6-methyladenosine (m6A) methylation
differential methylation peaks
MeRIP-seq
UPLC-QQQ-MS
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.735454/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.735454/full

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