Protective Effects against the Development of Alzheimer’s Disease in an Animal Model through Active Immunization with Methionine-Sulfoxide Rich Protein Antigen

The brain during Alzheimer’s disease (AD) is under severe oxidative attack by reactive oxygen species that may lead to methionine oxidation. Oxidation of the sole methionine (Met35) of beta-amyloid (A<i>β</i>), and possibly methionine residues of other extracellular proteins, may be one...

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Bibliographic Details
Main Authors: Adam S. Smith, Kyle R. Gossman, Benjamin Dykstra, Fei Philip Gao, Jackob Moskovitz
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/4/775