Single-exposure X-ray phase imaging microscopy with a grating interferometer

The advent of hard X-ray free-electron lasers enables nanoscopic X-ray imaging with sub-picosecond temporal resolution. X-ray grating interferometry offers a phase-sensitive full-field imaging technique where the phase retrieval can be carried out from a single exposure alone. Thus, the method is at...

Full description

Bibliographic Details
Main Authors: Andreas Wolf, Bernhard Akstaller, Silvia Cipiccia, Silja Flenner, Johannes Hagemann, Veronika Ludwig, Pascal Meyer, Andreas Schropp, Max Schuster, Maria Seifert, Mareike Weule, Thilo Michel, Gisela Anton, Stefan Funk
Format: Article
Language:English
Published: International Union of Crystallography 2022-05-01
Series:Journal of Synchrotron Radiation
Subjects:
Online Access:http://scripts.iucr.org/cgi-bin/paper?S160057752200193X
Description
Summary:The advent of hard X-ray free-electron lasers enables nanoscopic X-ray imaging with sub-picosecond temporal resolution. X-ray grating interferometry offers a phase-sensitive full-field imaging technique where the phase retrieval can be carried out from a single exposure alone. Thus, the method is attractive for imaging applications at X-ray free-electron lasers where intrinsic pulse-to-pulse fluctuations pose a major challenge. In this work, the single-exposure phase imaging capabilities of grating interferometry are characterized by an implementation at the I13-1 beamline of Diamond Light Source (Oxfordshire, UK). For comparison purposes, propagation-based phase contrast imaging was also performed at the same instrument. The characterization is carried out in terms of the quantitativeness and the contrast-to-noise ratio of the phase reconstructions as well as via the achievable spatial resolution. By using a statistical image reconstruction scheme, previous limitations of grating interferometry regarding the spatial resolution can be mitigated as well as the experimental applicability of the technique.
ISSN:1600-5775