Anti-malarial activity of geldanamycin derivatives in mice infected with <it>Plasmodium </it><it>yoelii</it>
<p>Abstract</p> <p>Background</p> <p>Geldanamycin (GA), a benzoquinone ansamycin antibiotic has been shown in vitro to possess anti-plasmodial activity. Pharmacological activity of this drug is attributed to its ability to inhibit PfHSP90. The parasite growth arrest has...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-02-01
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Series: | Malaria Journal |
Subjects: | |
Online Access: | http://www.malariajournal.com/content/11/1/54 |