Anti-malarial activity of geldanamycin derivatives in mice infected with <it>Plasmodium </it><it>yoelii</it>

<p>Abstract</p> <p>Background</p> <p>Geldanamycin (GA), a benzoquinone ansamycin antibiotic has been shown in vitro to possess anti-plasmodial activity. Pharmacological activity of this drug is attributed to its ability to inhibit PfHSP90. The parasite growth arrest has...

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Bibliographic Details
Main Authors: Mout Rubul, Xu Zhi-Dong, Wolf Angela K H, Jo Davisson Vincent, Jarori Gotam K
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Malaria Journal
Subjects:
Online Access:http://www.malariajournal.com/content/11/1/54