Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages

Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages

Dysregulation of cholesterol metabolism represents one of the major risk factors for atherosclerotic cardiovascular disease (CVD). Oxidized cholesterol esters (oxCE) in low-density lipoprotein (LDL) have been implicated in CVD but the underlying mechanisms remain poorly defined. We use a targeted li...

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Bibliographic Details
Main Authors: Shuyuan Guo, Jianhong Lu, Yujuan Zhuo, Mengqing Xiao, Xinli Xue, Shanshan Zhong, Xia Shen, Chunzhao Yin, Luxiao Li, Qun Chen, Mingjiang Zhu, Buxing Chen, Mingming Zhao, Lemin Zheng, Yongzhen Tao, Huiyong Yin
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718310851

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http://www.sciencedirect.com/science/article/pii/S2213231718310851

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