Systemic Inflammatory Mediators Are Effective Biomarkers for Predicting Adverse Outcomes in <named-content content-type="genus-species">Clostridioides difficile</named-content> Infection

Systemic Inflammatory Mediators Are Effective Biomarkers for Predicting Adverse Outcomes in <named-content content-type="genus-species">Clostridioides difficile</named-content> Infection

ABSTRACT Clostridioides difficile infection (CDI) can result in severe disease and death, with no accurate models that allow for early prediction of adverse outcomes. To address this need, we sought to develop serum-based biomarker models to predict CDI outcomes. We prospectively collected sera ≤48...

Full description

Bibliographic Details
Main Authors: Michael G. Dieterle, Rosemary Putler, D. Alexander Perry, Anitha Menon, Lisa Abernathy-Close, Naomi S. Perlman, Aline Penkevich, Alex Standke, Micah Keidan, Kimberly C. Vendrov, Ingrid L. Bergin, Vincent B. Young, Krishna Rao
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
biomarkers
Clostridioides difficile
Clostridium difficile
machine learning
predictive modeling
cytokines
Online Access:https://journals.asm.org/doi/10.1128/mBio.00180-20

Internet

https://journals.asm.org/doi/10.1128/mBio.00180-20

Similar Items