ZRC3308 Monoclonal Antibody Cocktail Shows Protective Efficacy in Syrian Hamsters against SARS-CoV-2 Infection

ZRC3308 Monoclonal Antibody Cocktail Shows Protective Efficacy in Syrian Hamsters against SARS-CoV-2 Infection

We have developed a monoclonal antibody (mAb) cocktail (ZRC-3308) comprising of ZRC3308-A7 and ZRC3308-B10 in the ratio 1:1 for COVID-19 treatment. The mAbs were designed to have reduced immune effector functions and increased circulation half-life. mAbs showed good binding affinities to non-competi...

Full description

Bibliographic Details
Main Authors: Pragya D. Yadav, Sanjeev Kumar Mendiratta, Sreelekshmy Mohandas, Arun K. Singh, Priya Abraham, Anita Shete, Sanjay Bandyopadhyay, Sanjay Kumar, Aashini Parikh, Pankaj Kalita, Vibhuti Sharma, Hardik Pandya, Chirag G. Patel, Mihir Patel, Swagat Soni, Suresh Giri, Mukul Jain
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
ZRC3308
SARS-CoV-2
monoclonal antibody
prophylaxis
hamsters
Online Access:https://www.mdpi.com/1999-4915/13/12/2424

Internet

https://www.mdpi.com/1999-4915/13/12/2424

Similar Items