The Apoe-/- Mouse PhysioLab® Platform: A Validated Physiologically-based Mathematical Model of Atherosclerotic Plaque Progression in the Apoe-/- Mouse

<em>Motivation:</em>Atherosclerosis is a complex multi-pathway inflammatory disease where accumulation of oxidatively modified lipids and leukocytes in the arterial intima leads to plaque formation over time. Translating Apoe&lt...

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Bibliographic Details
Main Authors: Jason R Chan, Gregory Vuillaume, Caitlin Bever, Stefan Lebrun, Michael Lietz, Yvonne Steffen, Katrin Stolle, Karim Wahba, Xiao Wang, Shonna Moodie, Julia Hoeng, Manuel C Peitsch, Lyn M Powell
Format: Article
Language:English
Published: Pensoft Publishers 2012-09-01
Series:BioDiscovery
Subjects:
Online Access:https://biodiscovery.pensoft.net/article/8929/download/pdf/