NeuroProtect, a Candidate Formula From Traditional Chinese Medicine, Attenuates Amyloid-β and Restores Synaptic Structures in APP/PS1 Transgenic Mice

NeuroProtect, a Candidate Formula From Traditional Chinese Medicine, Attenuates Amyloid-β and Restores Synaptic Structures in APP/PS1 Transgenic Mice

Background: Alzheimer’s disease (AD) is the most common cause of dementia. The emerging data suggest that cognitive decline occurred in the setting of Aβ accumulation with synaptic dysfunction, which started to happen at preclinical stages. Then, presymptomatic intervention is more critical to postp...

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Bibliographic Details
Main Authors: Yan Tan, Xu Wang, Jiani Zhang, Huawei Zhang, Haiyan Li, Tiantian Peng, Weihang Chen, Peng Wei, Zhaoheng Liu, Fang He, Jiao Li, Haimin Ding, Na Li, Zhaoyang Wang, Zhenqiang Zhang, Qian Hua
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
Aβ
Alzheimer’s disease
geniposide
Panax notoginseng saponins (PNS)
synaptic structure
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.850175/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.850175/full

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