Yiqi Jianpi Huayu Jiedu Decoction Inhibits Metastasis of Colon Adenocarcinoma by Reversing Hsa-miR-374a-3p/Wnt3/β-Catenin-Mediated Epithelial–Mesenchymal Transition and Cellular Plasticity

Yiqi Jianpi Huayu Jiedu Decoction Inhibits Metastasis of Colon Adenocarcinoma by Reversing Hsa-miR-374a-3p/Wnt3/β-Catenin-Mediated Epithelial–Mesenchymal Transition and Cellular Plasticity

Colon adenocarcinoma (COAD) accounts for 95% of colon cancer cases, with the 5-year survival rate significantly affected by local or distant metastases. Yiqi Jianpi Huayu Jiedu decoction (YJHJD), based on the theory of “nourish qi, invigorate the spleen, remove blood stasis, and detoxify”, has long...

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Bibliographic Details
Main Authors: Yuwen Zhuang, Jinyong Zhou, Shenlin Liu, Qiong Wang, Jun Qian, Xi Zou, Haiyan Peng, Tian Xue, Zhichao Jin, Cunen Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
Yiqi Jianpi Huayu Jiedu decoction
colon adenocarcinoma
epithelial–mesenchymal transition
cellular plasticity
hsa-miR-374a-3p
Wnt3
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.904911/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.904911/full

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