ATP-Binding and Hydrolysis in Inflammasome Activation

The prototypical model for NOD-like receptor (NLR) inflammasome assembly includes nucleotide-dependent activation of the NLR downstream of pathogen- or danger-associated molecular pattern (PAMP or DAMP) recognition, followed by nucleation of hetero-oligomeric platforms that lie upstream of inflammat...

Full description

Bibliographic Details
Main Authors: Christina F. Sandall, Bjoern K. Ziehr, Justin A. MacDonald
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/19/4572