Stability of Pharmaceutical Co-Crystals at Humid Conditions Can Be Predicted

Stability of Pharmaceutical Co-Crystals at Humid Conditions Can Be Predicted

Knowledge of the stability of pharmaceutical formulations against relative humidity (RH) is essential if they are to become pharmaceutical products. The increasing interest in formulating active pharmaceutical ingredients as stable co-crystals (CCs) triggers the need for fast and reliable in-silico...

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Bibliographic Details
Main Authors: Heiner Veith, Maximilian Zaeh, Christian Luebbert, Naír Rodríguez-Hornedo, Gabriele Sadowski
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceutics
Subjects:
cocrystal
disproportionation
stability
deliquescence
moisture sorption
PC-SAFT
Online Access:https://www.mdpi.com/1999-4923/13/3/433

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https://www.mdpi.com/1999-4923/13/3/433

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