Urinary Aromatic Amino Acid Metabolites Associated With Postoperative Emergence Agitation in Paediatric Patients After General Anaesthesia: Urine Metabolomics Study

Urinary Aromatic Amino Acid Metabolites Associated With Postoperative Emergence Agitation in Paediatric Patients After General Anaesthesia: Urine Metabolomics Study

Background: Emergence agitation (EA) is very common in paediatric patients during recovery from general anaesthesia, but underlying mechanisms remain unknown. This prospective study was designed to profile preoperative urine metabolites and identify potential biomarkers that can predict the occurren...

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Bibliographic Details
Main Authors: Yueyue Li, Jingjie Li, Yuhuan Shi, Xuhui Zhou, Wanqing Feng, Lu Han, Daqing Ma, Hong Jiang, Yongfang Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
aromatic amino acids
emergence agitation
metabolomics
paediatric anaesthesia
prediction model
urine neurotransmitters
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.932776/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.932776/full

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