3D‐Epigenomic Regulation of Gene Transcription in Hepatocellular Carcinoma

3D‐Epigenomic Regulation of Gene Transcription in Hepatocellular Carcinoma

Abstract The fundamental cause of transcription dysregulation in hepatocellular carcinoma (HCC) remains elusive. To investigate the underlying mechanisms, comprehensive 3D‐epigenomic analyses are performed in cellular models of THLE2 (a normal hepatocytes cell line) and HepG2 (a hepatocellular carci...

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Bibliographic Details
Main Authors: Yuliang Feng, Ping Wang, Liuyang Cai, Meixiao Zhan, Fan He, Jiahui Wang, Yong Li, Eva Gega, Wei Zhang, Wei Zhao, Yongjie Xin, Xudong Chen, Yijun Ruan, Ligong Lu
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Advanced Genetics
Subjects:
3D genome
3D‐epigeome
ChIA‐PET
chromatin topology
hepatocellular carcinoma
transcription regulation
Online Access:https://doi.org/10.1002/ggn2.202100010

Internet

https://doi.org/10.1002/ggn2.202100010

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