CD13 inhibition augments DR4-induced tumor cell death in a p-ERK1/2-independent manner
Objective: Death receptor 4 (DR4; TRAIL-R1) critically mediates extrinsic apoptosis cascades via binding to TNF-related apoptosis-inducing ligand (TRAIL). However, intrinsic and/or acquired resistance are observed in the clinical application of TRAIL. The aim of this study was to investigate the fun...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
China Anti-Cancer Association
2021-05-01
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| Series: | Cancer Biology & Medicine |
| Subjects: | |
| Online Access: | http://www.cancerbiomed.org/index.php/cocr/article/view/1812 |