G-protein coupled estrogen receptor (GPER1) activation promotes synaptic insertion of AMPA receptors and induction of chemical LTP at hippocampal temporoammonic-CA1 synapses

G-protein coupled estrogen receptor (GPER1) activation promotes synaptic insertion of AMPA receptors and induction of chemical LTP at hippocampal temporoammonic-CA1 synapses

Abstract It is well documented that 17β estradiol (E2) regulates excitatory synaptic transmission at hippocampal Shaffer-collateral (SC)-CA1 synapses, via activation of the classical estrogen receptors (ERα and ERβ). Hippocampal CA1 pyramidal neurons are also innervated by the temporoammonic (TA) pa...

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Detaylı Bibliyografya
Asıl Yazarlar: Leigh Clements, Amy Alexander, Kirsty Hamilton, Andrew Irving, Jenni Harvey
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2023-01-01
Seri Bilgileri:Molecular Brain
Konular:
Estrogen
GPER1
Synaptic transmission
AMPA receptor
Synaptic plasticity
Temporoammonic
Online Erişim:https://doi.org/10.1186/s13041-023-01003-3

Internet

https://doi.org/10.1186/s13041-023-01003-3

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