Chalcones as Anti-Glioblastoma Stem Cell Agent Alone or as Nanoparticle Formulation Using Carbon Dots as Nanocarrier

Chalcones as Anti-Glioblastoma Stem Cell Agent Alone or as Nanoparticle Formulation Using Carbon Dots as Nanocarrier

The current prognosis for glioblastoma is dismal. Treatment-resistant glioblastoma stem cells (GSCs) and the failure of most drugs to reach therapeutic levels within the tumor remain formidable obstacles to successful treatment. Chalcones are aromatic ketones demonstrated to reduce malignant propert...

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Bibliographic Details
Main Authors: Eduardo A. Veliz, Anastasiia Kaplina, Sajini D. Hettiarachchi, Athina L. Yoham, Carolina Matta, Sabrin Safar, Meghana Sankaran, Esther L. Abadi, Emel Kirbas Cilingir, Frederic A. Vallejo, Winston M. Walters, Steven Vanni, Roger M. Leblanc, Regina M. Graham
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
glioblastoma
nanocarrier
carbon dot
chalcone
drug delivery system
glioblastoma stem cell
Online Access:https://www.mdpi.com/1999-4923/14/7/1465

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https://www.mdpi.com/1999-4923/14/7/1465

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