Discrete states of a protein interaction network govern interphase and mitotic microtubule dynamics.

The cytoplasm of eukaryotic cells is thought to adopt discrete "states" corresponding to different steady states of protein networks that govern changes in subcellular organization. For example, in Xenopus eggs, the interphase to mitosis transition is induced solely by activation of cyclin...

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Bibliographic Details
Main Authors: Philipp Niethammer, Iva Kronja, Stefanie Kandels-Lewis, Sonja Rybina, Philippe Bastiaens, Eric Karsenti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1769425?pdf=render