Screening of selective histone deacetylase inhibitors by proteochemometric modeling

Screening of selective histone deacetylase inhibitors by proteochemometric modeling

<p>Abstract</p> <p>Background</p> <p>Histone deacetylase (HDAC) is a novel target for the treatment of cancer and it can be classified into three classes, i.e., classes I, II, and IV. The inhibitors selectively targeting individual HDAC have been proved to be the better...

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Bibliographic Details
Main Authors: Wu Dingfeng, Huang Qi, Zhang Yida, Zhang Qingchen, Liu Qi, Gao Jun, Cao Zhiwei, Zhu Ruixin
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Bioinformatics
Subjects:
Histone deacetylases inhibitors
Proteochemometric
Selective inhibitors
Online Access:http://www.biomedcentral.com/1471-2105/13/212

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http://www.biomedcentral.com/1471-2105/13/212

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