Anti-Scg3 Gene Therapy to Treat Choroidal Neovascularization in Mice

Anti-Scg3 Gene Therapy to Treat Choroidal Neovascularization in Mice

Neovascular age-related macular degeneration (nAMD) with choroidal neovascularization (CNV) is a leading cause of blindness in the elderly in developed countries. The disease is currently treated with anti-angiogenic biologics, including aflibercept, against vascular endothelial growth factor (VEGF)...

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Bibliographic Details
Main Authors: Chengchi Huang, Liyang Ji, Avinash Kaur, Hong Tian, Prabuddha Waduge, Keith A. Webster, Wei Li
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomedicines
Subjects:
age-related macular degeneration
choroidal neovascularization
gene therapy
secretogranin III (Scg3)
anti-Scg3 gene therapy
disease-targeted gene therapy
Online Access:https://www.mdpi.com/2227-9059/11/7/1910

Internet

https://www.mdpi.com/2227-9059/11/7/1910

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