Predicting conversion of brain β-amyloid positivity in amyloid-negative individuals

Predicting conversion of brain β-amyloid positivity in amyloid-negative individuals

Abstract Background Cortical deposition of β-amyloid (Aβ) plaque is one of the main hallmarks of Alzheimer’s disease (AD). While Aβ positivity has been the main concern so far, predicting whether Aβ (−) individuals will convert to Aβ (+) has become crucial in clinical and research aspects. In this s...

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Bibliographic Details
Main Authors: Chae Jung Park, Younghoon Seo, Yeong Sim Choe, Hyemin Jang, Hyejoo Lee, Jun Pyo Kim, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Dementia
Amyloid PET
Prediction model
Machine learning
Online Access:https://doi.org/10.1186/s13195-022-01067-8

Internet

https://doi.org/10.1186/s13195-022-01067-8

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