Genetic variations of EBV-LMP1 from nasopharyngeal carcinoma biopsies: potential loss of T cell epitopes

Genetic variations of EBV-LMP1 from nasopharyngeal carcinoma biopsies: potential loss of T cell epitopes

To find Epstein-Barr virus (EBV) strains with genetic variations of EBV latent membrane protein 1 (EBV-LMP1) from nasopharyngeal carcinoma (NPC), the full-length DNA of LMP1 genes from 21 NPC biopsies obtained in Hunan province in southern China was amplified and sequenced. Our sequences were compar...

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Bibliographic Details
Main Authors: Y.L. Tang, J.H. Lu, L. Cao, M.H. Wu, S.P. Peng, H.D. Zhou, C. Huang, Y.X. Yang, Y.H. Zhou, Q. Chen, X.L. Li, M. Zhou, G.Y. Li
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2008-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Genetic variation
Epitope
Immune recognition
Latent membrane protein 1
Tumorigenicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000200006

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000200006

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