VSP-2 attenuates secretion of inflammatory cytokines induced by LPS in BV2 cells by mediating the PPARγ/NF-κB signaling pathway

VSP-2 attenuates secretion of inflammatory cytokines induced by LPS in BV2 cells by mediating the PPARγ/NF-κB signaling pathway

Neuroinflammation, characterized by microglial activation and the subsequent secretion of inflammatory cytokines, plays a pivotal role in neurodegenerative diseases and brain injuries, often leading to neuronal damage and death. Alleviating neuroinflammation has thus emerged as a promising strategy...

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Bibliographic Details
Main Authors: Cui Jingxin, Xu Liwei, Sun Yimeng, Dai Lingfei, Mo Yuxiu, Yun Keli, Chen Yifei, Chen Linglin
Format: Article
Language:English
Published: De Gruyter 2024-04-01
Series:Open Life Sciences
Subjects:
neuroinflammation
vsp-2
proinflammatory cytokines
nf-κb pathway
pparγ
Online Access:https://doi.org/10.1515/biol-2022-0861

Internet

https://doi.org/10.1515/biol-2022-0861

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