Inferring metabolic phenotypes from the exometabolome through a thermodynamic variational principle

Networks of biochemical reactions, like cellular metabolic networks, are kept in non-equilibrium steady states by the exchange fluxes connecting them to the environment. In most cases, feasible flux configurations can be derived from minimal mass-balance assumptions upon prescribing in- and outtake...

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Bibliographic Details
Main Authors: Daniele De Martino, Fabrizio Capuani, Andrea De Martino
Format: Article
Language:English
Published: IOP Publishing 2014-01-01
Series:New Journal of Physics
Subjects:
Online Access:https://doi.org/10.1088/1367-2630/16/11/115018