Huoxiang Zhengqi alleviates azoxymethane/dextran sulfate sodium-induced colitis-associated cancer by regulating Nrf2/NF-κB/NLRP3 signaling

Huoxiang Zhengqi alleviates azoxymethane/dextran sulfate sodium-induced colitis-associated cancer by regulating Nrf2/NF-κB/NLRP3 signaling

Colitis-associated cancer (CAC) is a subtype of inflammatory bowel disease (IBD)-associated colorectal cancer. Huoxiang Zhengqi (HXZQ) is a classical Chinese herbal medicine and has been used to treat intestinal disorders, however, anti-CAC effects and underlying mechanisms of HXZQ have not been rep...

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Bibliographic Details
Main Authors: Mingyuan Dong, Honghan Liu, Tianjiao Cao, Lanzhou Li, Zhen Sun, Ye Qiu, Di Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Huoxiang Zhengqi
colitis-associated cancer
intestinal microbiota
metabolomics
Nrf2/NF-κB/NLRP3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1002269/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1002269/full

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