Computational Docking Study of p7 Ion Channel from HCV Genotype 3 and Genotype 4 and Its Interaction with Natural Compounds.

BACKGROUND:The current standard care therapy for hepatitis C virus (HCV) infection consists of two regimes, namely interferon-based and interferon-free treatments. The treatment through the combination of ribavirin and pegylated interferon is expensive, only mildly effective, and is associated with...

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Bibliographic Details
Main Authors: Shilu Mathew, Kaneez Fatima, M Qaiser Fatmi, Govindaraju Archunan, Muhammad Ilyas, Nargis Begum, Esam Azhar, Ghazi Damanhouri, Ishtiaq Qadri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126510